Our lab studies metabolism, which is foundational to all of life and underpins key areas of biology including synthetic biology, human health, stress tolerance, and aging. There are numerous genes of unknown function that are predicted to play some kind of role in metabolism. We use a variety of bioinformatic and comparative genomics tools to predict the metabolic function of unknown genes. These predictions are then tested using biochemical and genetic techniques such as phenotypic analysis of knockouts in model plant and/or microbial organisms, assaying recombinant enzymes, metabolomics, etc. In addition to performing cutting-edge science, students in our lab will develop communication and collaboration skills that will prepare them for exciting careers in industry or academia. Read more about research in the Niehaus lab and current projects and feel free to contact us with any questions!